商品描述

伏苓(萃取液)

一、Introductiom:

.English name:

Glabrous Greenbrier

.Learn    :

Smilax glabra Roxb.

.Section    :

The section of Ba Qi(Smilacaceae) Ba Qi belongs to(Smilax) or bulb of lily section

.Do not    Call:

The Hou hull stabs(Taiwan), the cold rice regiment, red clay Ling, mountain pig feces, hair tail Shu, mountain Yi food, mountain is strange and good.The mountain returns, soil Fu, ground Fu Ling, grass Yu surplus grain, stab pig Ling, hard rice head, light leaf Ba Qi.

.Sex form:Straighten a plant

.Produce ground at first:

River valley in Yangtze River with south each province area.India, Vietnam, Thailand

.Divide into cloth:Was born in slope a wood to descend, the wayside bush and valley facing the sun

. Elevation height:Elevation 0-800 meters of elevations 800-1800 meters

.Use  Way:

1、 The medicine uses:

Many hole germ section fungi Fu Ling Poria cocos( Schw.) Wolf germ the white part of the pitSex is sweet and thin, even.The pure heat counteracts poison, the benefit is wet.The lord cures hook to carry the helicoid disease, syphilis, the rheumatism joint pain, the Yong Jie swollen poison, eczema, the skin Yan, the mercury powder, the silver is chronic poisoned.

.Leaf:

The single leaf gets with each other, the Ge quality, the long circular goes to an oval form to cover with the needle form, growing 5-12 cm, breadth 1-5 cm, carry first gradually sharp, the Ji department circle or the Xie form, whole good luck, surface green, have white powder below, the main vein is 3 obvious, thin vein net;The petiole grows 1-2 cm, Tuo the leaf change into 2 volume beards.

.Flower:

Open a small white flower during 7-8 months, spend list, bisexual and different stub, get the umbrella form inflorescence for the Yi, the inflorescence Geng is very short, growing 0.1-0.3 cm, the small flower stalk is slender, growing 1-1.7 cm, the Ji department contain the triangle small Bao slice that several Xius save.The perianth Lie slice 6, chaise;Stamen 6, to compare with the flower medicine, the filament is short;The ovary place of honor, 3 rooms, the column head 3, slightly anti- song.Spend a green white.The flower expects 7 go to November.

.Caulis:

Climb the Yuan bush, the caulis didn't stab.Root the form caulis is horizontal to get in soil in, thin long, get most root of whiskerses, separate each time a be apart from to get a form knot stanza, piece root the form root the form caulis grow 5-15 cm, diameter 2-5 cm, thorough soil in can reach to a meter of remaining, quality rather solid, the cortex is strong and tough, brown, cave and convex gravamen, inside face the meat quality powder, yellow white, spread densely a pale red color a little bit small.

.Fruit  Solid:

The berry spheroid, familiar hour purple black, outside white powder.Expect as a result 11 go to April.

.Especially Sex:

Climb the good luck bush, high 1-4 meters.The root-stock irregularity knots the stanza form, fatty and thick, the surface is dark brown, the quality is hard, inside face powder meat quality.Leaf thin Ge quality, the Gen gets, the oval form covers with the needle form, 6-15 cm, breadth 1-7 cm, the leaf faces deeply green, leaf carry the powder white on leaf's back, leaf Yi often has two volume beards.Spending the list gets, bisexual and different stub, green white, six Leng form spheroids, diameter about 0.3 cm, usually more than ten rows become the umbrella form inflorescence, male flowers outside, inside round the perianth slice is each 3, and pistillate flower size likeness.The berry spheroid, diameter 0.7-1 cm, the mature hour is purple black, have powder frost.Medicine's using the soil Fu Ling is to make use of the soil Fu Ling(light leaf the Ba Qi) Smilax glabra Roxb.Of piece root the form root form caulis.

二、Apply:

In order to live on in the germ pit of many hole germ section fungi Fu Ling of the pine root, the Fu Ling the part used is different, its function is also different

The black and brown cortex that the germ checks goes into the medicine the Fu Ling skin, the longer than benefit water decreases swelling, curing skin edema more

The skin layer under of red part go into the medicine red Fu Ling, the longer than pure benefit is damp and hot, the lord cures a water wet be partial to the heat

Germ pit inner part white part go into medicine understand the Fu Ling, longer than benefit of Jian Pi is wet, the lord cures Pi falsely wet prosperous

Bring white part of having the pine root Fu God into the medicine, there is to embrace the wood God, longer than feel at ease God rather, cure mind particularly uneasy, shock, forgetful, the pine root in the germ pit go into the medicine Fu divine tree, the longer than even liver tranquilizes the nerves

【Clinical application 】

1:Be used for urinating disadvantage, edema etc. the disease Fu Ling function benefit water Shen is wet, and the medicine Ping-ho, the benefit water and don't harm sense of right.

2:Be used for Pi falsely Xie Xie.

3:Being used for the phlegm drinks a cough.

4:Be used for heart palpitates, suffer from insomnia etc. the disease Fu Ling can cultivate mental calm to tranquilize the nerves, so can be used for mind uneasy, heart palpitates, suffer from insomnia etc. disease.

【Pharmacology function 】

1:The benefit urines a function:The Fu Ling benefit urine machine becomes not clears, and the compound prescribe more single flavor medicine function is obvious.

2:Quiet function in town:The Fu Ling fries to inject to the small rat belly cavity, can repress a self-moving activity,

Also can resist caffeine with the result that the small rat excitement excessiveness, compare secure anaesthesia to have already been in conjunction with a function to Ba.

3:Cardiovascular system:the ethanol withdraw a thing to make the myocardial constringency power strengthen, the heart rate increases.

4:Digestive system:the Fu Ling for four chlorination carbons cause of the small rat liver hurt, there is obvious protection function.

5:The anti- tumor function:the Fu Ling have another sugar to have already repressed a function to the small rat tumor, its function has something to do with thymus gland, can activate part to repair a body

三、Research:

1, the Fu Ling(the Poria cocos) uses one of the mushroom germ for the my country important medicine.This research takes the Fu Ling germ pit as material, falling in pieces through the raw material of Fu Ling, the ammonium sulfate egg white precipitate and dialysis gain thick protein to extract a liquid after, again is exchanged with anion DE-52 and the FPLC layer Xi turn concentrated purely and get the immunity of Fu Ling regulate egg white PCP.The gum body filters the tube column layer Xi manifestation, the Fu Ling egg white PCP molecular weight about 35.6 kDas;Was measured by the protein gum body electricity Yong analysis the Fu Ling egg white PCP has two unit egg whites, its molecular weight about the 14.3 kDas and the 20.3 kDas.In wait for an electricity to focus electricity Yong to find its pI a value about 5.2, and obtain the An Ji of the Fu Ling egg white PCP sour constitute and two N of the unit egg whites-carry a sour sequence of the An Ji.

On the other hand, making use of the cell fusion technique to manufacture to pay 3 stubs can recognize the single stub antibody of the Fu Ling egg white PCP, confirming its antibody further with single mind sex, antibody second type and antigen decision area, and in order to prevent the epidemic disease organization dye the method detect to know, the Fu Ling egg white PCP mainly is expressed in the parts such as cell wall, cell membrane and cell nucleus etc.s of the hypha of Fu Ling in.

Immunity outside the body regulates experiment detection, the Fu Ling egg white PCP can activate RAW directly 264.7 huge bite cell to secrete the nitric oxide(NO) and TNF-a, all have obvious result, also raise huge bite the iNOS, TNF-a, b IL-1, IL-6, IL-12 of the cell and the performance of the mRNAs IL-18s, experiment to show the exclusion Fu Ling egg white P in the PMB and the LAL

In addition, the Fu Ling egg white PCP can stimulate lymphoid cell of small rat it increase to get and the cell metabolize an activity, also raising the cell hormone IFN-g to secrete quantity;The flow type cell analysis result manifestation, the Fu Ling egg white PCP can by raise a period cell comparison of the lymphoid cell S and G2/M, with reach to promote the T cell and the B cell it increase to get, and the mRNA of the adjustable stanza IL-2, IL-4, IL-5, IFN-g express quantity, however the Fu Ling egg white PCP can promote the IFN-g secrete, but will not produce the cell hormone IL-4, by above-mentioned result manifestation, the Fu Ling egg white PCP can activate the small rat Pi cell, and the first step calculate it and can urge the T cell to divide into Th1 cell.

2, announce to public the effect of the Fu Ling many sugar anti- tumor of the chemistry modifier.Method:?The Fu Ling that chemistry polishes has another sugar:Use 0.9% NaCl aqueous solutions to withdraw many sugar from the hypha body of the Fu Ling, was acetified by sulfuric acid, acquire the Fu Ling that the sulfuric acid acetifies many sugar.?The animal tests:Sarcoma 180 tumor cell(each time only 5 × 10^6)s inoculate in 7~8 the BaIB/c of the back skin of the small rat bottom, then be divided into the Fu Ling many sugar a treatment a set random, 5-the Fu male matched control and the PBS buffer aqua feminine gender matched control, each 10.Carrying on the belly cavity injects, continuing to inject a 7 ds.?Examination:After the last one time inject the 2 ds sentence to death small rat, slicing to take tumor, weighing, calculating to suppress the lump rate, and carrying on a histology observation to the tumor organization, liver, kidney and Pi etc..Result:?5-the Fu tumor repress the rate as 46%, through the chemistry modifier of Fu Ling many sugar repress the rate as 38.39%.?The histology observation shows that the Fu Ling many sugar treatment set it is thus clear that go to the tumor cell become the slice is bad to die area, also it is thus clear that check dyeing quality concentrated, the side gathers, even is the half month form, explain the tumor cell of bad the dead exist with the Diao Wu in the meantime.The histology observation also shows, through the chemistry modifier of Fu Ling many sugar has no obvious histology damage to the liver, kidney;And the masculine gender and the feminine gender matched control comparison, the Fu Ling many sugar treatment set the spleen Pi minor point of conduct of the small rat is clear, Pi central artery surroundings the lymphoid cell of the lymphoid sheath intensive, express to the protection function of the Pi.Conclusion:The Fu Ling that chemistry polishes has another sugar 180 tumor cells to have already killed harm and induce the Diao Wu to the small rat Sarcoma of function, and have to build up to the machine body immunity power

四、Effect：

The Fu Ling is the history of the traditional health care health function

(A)someone's way of keeping good health to the queen mother of Ci Xi, take the longevity benefit prescription drug to carry on a research, finds the in common use benefit Chinese herbal medicine has 64 kinds of, and utilization rate the highest Chinese herbal medicine would be the Fu Ling, having 78%, just is the white Zhu and Chinese angelica one by one in order.

(Two)the Manchu Dynasty is widely accepted to eat the Fu Ling Gao(cake) to make breakfast, also often making the cake of Fu Ling inside clip a candied fruit, the pine kernel, sweet joss-stick tasty rich in nourishment, Be that the Peking Man donates old-age friends and relatives speciality.

(Three)one of Song generation brotherses with the Su's author, took the Fu Ling because of getting sick, so recommended everyone take and write an article and can know.Su Zhe wears to have 《take the Fu Ling to endow with 》, Su the east ascent 《the east ascent is miscellaneous to record 》also carry to take the method of Fu Ling.The east ascent the Sir think the physical strength of his east ascent cake(contain the sesame and white Mi) food not Shuai, 100 diseases from go to, grow to get to want Jue.

By above-mentioned explain 2:00, the Fu Ling Be food and postpone a year for the health care food, want in the food to find out a similar a Chinese herbal medicine a treatment function almost seldom seen, so call it is the strange Pa in the food, a point also not for lead.

The chemistry of Fu Ling main composition

The chemistry of Fu Ling the main composition gathers carbohydrate for the variety, but main gather sugar(pachyman) for the Fu Ling, in addition, other next in importance composition contents are low but have the pharmacology activity then for solid Chun.(text inside call the vegetable of Fu Ling, actual is wool solid Chun or open solid Chun of the wreath wool)China produces Fu Ling in Yunnan the main solid Chun composition contain the pachymic acid, the tumulosic acid, the polyporenic acid c, 3-the epidehydrotumulosic acid is four kinds of, other solid Chun compositions are all very little, the composition is ofer no account, having the wheat corn solid Chun, protein, egg Lin fat, adenine, Dan alkali, set the ammonia is sour, the fatty acids and some inorganic matters, on science study what to speak of often is above-mentioned to gather carbohydrate and solid Chun.

(A)anti- inflammation function, is induced with the TPA compound of impatient or chronic inflammation respond manifestation the Fu Ling vegetable, opposite isn't inferior to in the anti- inflammation medicine indomethacin and the solid Chun anti- inflammation medicine Dexametasone milli-, this interpretable Chinese medicine is some standpoints, inflammation respond at the Chinese medicine medicine is a kind of go to wet reaction, namely above-mentioned human body humidity absorb, distribute and metabolize in have influence, the Fu Ling has influence deeply for Chinese herbal medicine of the head choose medicine, this kind of Fu Ling with interpretable function why be used for rheumatism pain, the lung department the infection cause inflammation(the phlegm have another and the phlegm cause a cough more) or Bi urine the system infection to cause a row the urine difficulty...Wait for.

(Two)the animal experiment manifestation Fu Ling the plain composition can reduce the diabetes of the second type, this also confirms the Fu Ling origin the grass outline jot down it eliminate a thirsty disease treatment.

(Three)the Fu Ling extract a thing and can enhance sea horse to deliver the long time distance to strengthen(LTP, the Long term potentiation) a signal through taking orally, this LTP(in the brain sea horse area) is thought by the scholar recently is remember an activity with the learning of the human body closely related, the Japanese scientist confirms the ginseng and the Fu Ling all has this function, this agrees with"happy(point a brain) the benefit ambition, forgetful" of the Fu Ling treatment use that this grass outline jots down to match.

(Four)the vegetable of Fu Ling have vomit a function;The Japanese scholar research turns purely behind the vegetable of Fu Ling or its chemistry derivatives are total 17s, causing animal to vomit phenomenon to have arrestment or delaying an effect to the cupric sulfate, this also confirms this grass Fu Ling that the outline jots down has "open stomach Ou negative".

(Five)the cancer prevent a medicine(the Cancer chemopreventive agents):Will need a cancer to promote in the chemistry carcinogen cause the cancer cell formation process this stage of function, the vegetable of Fu Ling has already repressed this stage function, having Japanese patent as on the 9025232th, on the 9176184th and the cultural heritage report to sue.

(Six)the anti- tumor function/anti-cancer function:The Japanese scholar finds the Fu Ling gathers the sugar composition contain the Jie anti- rat tumor result, mainland scholar then finds the result that the vegetable of Fu Ling has a function(the Synergistic effect) of join force and makes the cancer chemistry treatment medicine curative effect to build up.

(Seven)the immunity strengthen a function:The Taiwanese scholar extracts a thing with the Fu Ling to the list pit ball in person's blood to make a body to test outside, find the to build up immunity power function, this function through the cell hormone(cytokine) and reach, mainland scientist finds the part turns purely of the vegetable of Fu Ling also has the immunity to build up function.

(Eight)anti- oxygenation。

(Nine)cure a deaf function:The Fu Ling extracts a thing to the animal deaf caused by antibiotic toxicity function(Kanamycin), having already resisted a function, this kind of function also jots down in this grass outline.

(Ten)other functions:The indirect data can get the Fu Ling to have following and some pharmacology functions still from mainland reference book, if the benefit urines the protection function, the anti-cancer medicine wreath phosphoric acid An that the function, anti- ulcer function, compound causes hepatitis to cause a leukocyte decrease disease, town quiet function.

Oxidize how to cause

Person by breathing of action, absorb the oxygen in the air, carry on various operations of functions inside the body, is the material that maintains the life indispensability, but we inhale oxygen in the body about there is 2% will change live oxygen, it is a kind of instability of oxygen numerator, it will cause with the various material occurrence reaction in the body to oxidize, in the live oxygen this kind of material that causes to oxidize between the cell again be called "free radicals".

Free radicals

Talking to"oxidize" has to talk "free radicals" Free radical, the so-called free radicals is the numerator that brings the list electronics call free radicals, electronics original will run about, project light upon in the ray particularly, the metals ion catalyst, the miscellaneous quality is more or have …wait for condition under, accelerate creation free radicals more easily.The life of the general free radicals is for an instant just, after it robbed the other people's electronics, the oneself is settled down, the numerator that changes to rob to the electronics becomes a free radicals.

In addition, living will also accelerate cell to oxidize in still having already allowed much more factor, making the free radicals flee in the body internal rebellion as:Ultraviolet ray, project line, smoke to drink, the exercise excessiveness, nervous pressure, edible the excessive processed food and the excessive intake of the grease, these factor also all is accelerate an aging cause.When the cell occurrence oxidizes will cause skin of aging as:Crease, spot, pimple...etc., the inside organ and blood vessel would also produce because of oxidizing aging and the decline of the function is the main reason that causes the far-gone adult of afferent disease, high blood pressure, glycouria of heart get sick.

Anti- oxidizing agent

The anti- oxidizing agent is a kind of special chemistry material, as figure a, its ability and the free radicals function and fixed a free radicals, it because of without a H+ and became a free radicals.But the anti- oxidizing agent have a special ability to fix to become not to the electronics, this orbit that is because of this compound numerator structural allows a fixed resonance to appear.All anti- oxidizing agents,such as Ethoxyquin, BHT, , the BHA all has this characteristic.Once the anti- oxidizing agent released H+ no longer had the ability that the anti- oxidizes.If the quantity of the anti- oxidizing agent is low in the free radicals, then oxidizing still will continue to carry on.

This kind of live oxygen is an in the human body while breathing air, or when the food conversion become energy and will become in the meantime, mankind since want to depend on oxygen unavoidable and this type of oxidize respond and free radicals of creation, the not so bad human body can become an anti- to oxidize enzyme(SOD, GSH etc.), there is basic anti- to oxidize the function existence, this enzyme synthesizes to need to depend on a great deal of amino acids, so appropriate of take protein is necessary.